The focus for 2025 will be on structural heart disease with a focus on interventions and advances in that field. More than half of the Snowmass Cardiovascular attendees return, a testament to the excellent quality of the conference which has more than a 50-year history. If you are a first-time attendee, you will find a unique conference that features state-of-the-art knowledge aligned with practical decision-making set in an interactive program that includes discussions, case presentations, and debates. The faculty, comprising renowned experts and investigators, will offer insights and practical clinical advice for dealing with common cardiovascular problems incorporating the latest research and clinical guidelines focusing on the last two years.